Wen-Hung Chung Selected Research

Carbamazepine (Tegretol)

1/2022	An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice.
1/2020	Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions.
1/2020	Drug hypersensitivity reactions in Asia: regional issues and challenges.
11/2019	HLA-B*57:01 confers genetic susceptibility to carbamazepine-induced SJS/TEN in Europeans.
1/2019	Identification of drug-specific public TCR driving severe cutaneous adverse reactions.
1/2019	Controversies in drug allergy: Testing for delayed reactions.
1/2017	HLA Association with Drug-Induced Adverse Reactions.
7/2016	Severe cutaneous adverse drug reactions.
2/2014	Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: strength and clinical correlations.
6/2012	Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.

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Wen-Hung Chung Research Topics

Disease

46	Stevens-Johnson Syndrome (Lyell's Syndrome) 01/2023 - 04/2004
27	Hypersensitivity (Allergy) 05/2022 - 01/2002
24	Cicatrix (Scar) 01/2022 - 03/2005
19	Exanthema (Rash) 01/2022 - 11/2011
15	Eosinophilia 12/2021 - 11/2011
14	Drug Hypersensitivity (Drug Allergy) 01/2022 - 08/2007
13	Drug-Related Side Effects and Adverse Reactions 01/2022 - 08/2005
13	Drug Hypersensitivity Syndrome 12/2021 - 03/2005
10	Neoplasms (Cancer) 10/2021 - 04/2014
9	Genetic Predisposition to Disease (Genetic Predisposition) 01/2022 - 03/2005
8	Infections 10/2022 - 05/2014
8	Inflammation (Inflammations) 10/2021 - 09/2013
7	Blister (Bulla) 10/2022 - 12/2008
6	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 07/2008
6	Acute Generalized Exanthematous Pustulosis 09/2020 - 09/2010
5	Vitiligo 10/2022 - 08/2020
4	Necrosis 08/2017 - 12/2010
4	Gout 01/2017 - 03/2005
4	Hyperuricemia 01/2016 - 03/2005
3	Neoplasm Metastasis (Metastasis) 12/2021 - 01/2017
3	Pain (Aches) 02/2021 - 01/2014
3	Alopecia (Baldness) 08/2020 - 04/2014
2	Septic Shock (Toxic Shock Syndrome) 09/2022 - 10/2018
2	Gastrointestinal Hemorrhage (Hematochezia) 01/2022 - 01/2018
2	Paronychia 02/2021 - 03/2020
2	Fever (Fevers) 01/2021 - 01/2021
2	Melanosis (Freckles) 01/2021 - 08/2020
2	Anaphylaxis (Anaphylactic Shock) 01/2021 - 01/2018
2	Drug Eruptions (Drug Eruption) 01/2021 - 07/2016
2	Leprosy (Hansen's Disease) 01/2021 - 01/2018
2	Epilepsy (Aura) 08/2020 - 04/2013
2	Skin Diseases (Skin Disease) 08/2020 - 01/2008
2	Chronic Renal Insufficiency 01/2020 - 08/2017
2	Urticaria (Hives) 10/2019 - 01/2018
2	Gouty Arthritis 01/2019 - 01/2017
2	Wounds and Injuries (Trauma) 01/2019 - 11/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 09/2015
2	Disease Progression 10/2018 - 01/2017
2	Chemical and Drug Induced Liver Injury 01/2017 - 01/2014
1	Trichiasis 01/2023
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2023
1	Keratitis 01/2023

Drug/Important Bio-Agent (IBA)

49	Pharmaceutical PreparationsIBA 01/2022 - 04/2004
26	HLA-B Antigens (HLA-B)IBA 01/2022 - 04/2004
17	Allopurinol (Remid)FDA LinkGeneric 01/2022 - 03/2005
17	Carbamazepine (Tegretol)FDA LinkGeneric 01/2022 - 04/2004
13	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 04/2004
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2008
8	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 04/2006
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 03/2010
6	CytokinesIBA 01/2022 - 09/2013
6	abacavir (Ziagen)FDA Link 01/2022 - 08/2007
6	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 12/2011
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2011
5	ChemokinesIBA 01/2022 - 09/2013
5	Genetic Markers (Genetic Marker)IBA 01/2022 - 04/2004
5	Cytochrome P-450 CYP2C9IBA 01/2022 - 07/2016
5	Phenytoin (Dilantin)FDA LinkGeneric 01/2022 - 08/2014
4	Immunoglobulin E (IgE)IBA 05/2022 - 01/2020
4	Febuxostat FDA Link 01/2022 - 09/2015
4	HLA-B57 antigenIBA 01/2022 - 01/2019
4	EnzymesIBA 01/2022 - 11/2016
4	Uric Acid (Urate)IBA 10/2021 - 01/2017
4	Immune Checkpoint InhibitorsIBA 10/2021 - 10/2019
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2011
4	AntigensIBA 01/2018 - 09/2013
4	Peptides (Polypeptides)IBA 01/2018 - 03/2005
3	SteroidsIBA 01/2023 - 01/2019
3	ErbB Receptors (EGF Receptor)IBA 02/2022 - 03/2020
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2018
3	Dapsone FDA Link 01/2022 - 01/2018
3	HLA-A31 antigenIBA 01/2022 - 02/2014
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021 - 03/2010
3	Oxypurinol (Oxipurinol)IBA 01/2016 - 09/2015
2	Oxcarbazepine (Trileptal)FDA LinkGeneric 09/2022 - 01/2017
2	VaccinesIBA 05/2022 - 01/2018
2	Etanercept (Enbrel)FDA Link 01/2022 - 01/2018
2	Granzymes (Granzyme)IBA 01/2022 - 01/2021
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 01/2009
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2022 - 01/2021
2	Betaxolol (Kerlon)FDA LinkGeneric 02/2021 - 03/2020
2	Antineoplastic Agents (Antineoplastics)IBA 02/2021 - 01/2018
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021 - 01/2019
2	Immunologic Factors (Immunomodulators)IBA 01/2021 - 10/2018
2	SulfonamidesIBA 01/2021 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2020 - 05/2017
2	Contrast MediaIBA 10/2020 - 01/2020
2	Penicillins (Penicillin)FDA Link 01/2020 - 05/2014
2	16S Ribosomal RNAIBA 01/2020 - 01/2018
2	Levamisole (Decaris)FDA Link 10/2018 - 01/2008
2	MelatoninIBA 10/2017 - 01/2017
2	perforin-granzyme BIBA 06/2012 - 12/2008
1	Anti-Infective Agents (Microbicides)IBA 10/2022
1	Amikacin (A.M.K)FDA LinkGeneric 10/2022
1	Linezolid (Zyvox)FDA Link 10/2022

Therapy/Procedure

17	Therapeutics 10/2022 - 03/2010
3	Immunotherapy 10/2019 - 01/2018
2	Oral Administration 01/2019 - 11/2014
2	Drug Therapy (Chemotherapy) 01/2018 - 01/2009
1	Transplantation 10/2022